Linear ion trap fabricated using rapid manufacturing technology

Linear ion trap fabricated using rapid manufacturing technology.

This article presents the design, construction, and test results of a linear ion trap, fabricated using digital light processing (DLP), which is a low-cost 3D layer-based manufacturing technique. The ion trap was incorporated into a portable mass spectrometer system and experimental mass spectrum was obtained for methamphetamine (m/z 182), cocaine (m/z 304), and rhodamine B (m/z 443), with a ma...

Micro-fabricated stylus ion trap.

An electroformed, three-dimensional stylus Paul trap was designed to confine a single atomic ion for use as a sensor to probe the electric-field noise of proximate surfaces. The trap was microfabricated with the UV-LIGA technique to reduce the distance of the ion from the surface of interest. We detail the fabrication process used to produce a 150 μm tall stylus trap with feature sizes of 40 μm...

Miniaturized Linear Wire Ion Trap Mass Analyzer.

We report a linear ion trap (LIT) in which the electric field is formed by fine wires held under tension and accurately positioned using holes drilled in two end plates made of plastic. The coordinates of the hole positions were optimized in simulation. The stability diagram and mass spectra using boundary ejection were compared between simulation and experiment and good agreement was found. Th...

"Product ion monitoring" assay for prostate-specific antigen in serum using a linear ion-trap.

While numerous strategies exist for biomarker discovery, the bottleneck to product development and routine use at the clinic is in the verification phase of candidate biomarkers. The aim of this study was to establish a robust and high-throughput product ion monitoring (PIM) assay that is potentially capable of rapidly verifying candidates from discovery phase experiments. Using prostate-specif...

Using AP-MALDI Ion Trap Mass Spectrometry